| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lbys_2465 | Lbys_2466 | Lbys_2465 | Lbys_2466 | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | 0.808 |
| Lbys_2465 | Lbys_2467 | Lbys_2465 | Lbys_2467 | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | 0.780 |
| Lbys_2465 | Lbys_2468 | Lbys_2465 | Lbys_2468 | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | Glucose-1-phosphate cytidylyltransferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR013446:IPR005835; KEGG: bfs:BF2603 putative LPS biosynthesis-related sugar-phosphate nucleotidyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate cytidylyltransferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase. | 0.748 |
| Lbys_2465 | Lbys_2469 | Lbys_2465 | Lbys_2469 | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: hmo:HM1_1228 glycosyl transferase, group 2 family protein, putative; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, group 1/2 family protein; PFAM: Glycosyl transferase family 2. | 0.620 |
| Lbys_2465 | gmd | Lbys_2465 | Lbys_2464 | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.599 |
| Lbys_2466 | Lbys_2465 | Lbys_2466 | Lbys_2465 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | 0.808 |
| Lbys_2466 | Lbys_2467 | Lbys_2466 | Lbys_2467 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | 0.865 |
| Lbys_2466 | Lbys_2468 | Lbys_2466 | Lbys_2468 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | Glucose-1-phosphate cytidylyltransferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR013446:IPR005835; KEGG: bfs:BF2603 putative LPS biosynthesis-related sugar-phosphate nucleotidyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate cytidylyltransferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase. | 0.868 |
| Lbys_2466 | Lbys_2469 | Lbys_2466 | Lbys_2469 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: hmo:HM1_1228 glycosyl transferase, group 2 family protein, putative; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, group 1/2 family protein; PFAM: Glycosyl transferase family 2. | 0.611 |
| Lbys_2466 | gmd | Lbys_2466 | Lbys_2464 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.703 |
| Lbys_2466 | rpsC | Lbys_2466 | Lbys_1824 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.616 |
| Lbys_2466 | rpsL | Lbys_2466 | Lbys_1936 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.583 |
| Lbys_2466 | rpsN | Lbys_2466 | Lbys_1817 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.581 |
| Lbys_2466 | rpsQ | Lbys_2466 | Lbys_1821 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.577 |
| Lbys_2466 | rpsS | Lbys_2466 | Lbys_1826 | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.615 |
| Lbys_2467 | Lbys_2465 | Lbys_2467 | Lbys_2465 | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: cno:NT01CX_1528 glycosyl transferase, group 1 family protein, putative; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; PFAM: Glycosyl transferases group 1. | 0.780 |
| Lbys_2467 | Lbys_2466 | Lbys_2467 | Lbys_2466 | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | NAD-dependent epimerase/dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR020904:IPR001509; KEGG: cth:Cthe_2558 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-binding protein; PFAM: NAD dependent epimerase/dehydratase family. | 0.865 |
| Lbys_2467 | Lbys_2468 | Lbys_2467 | Lbys_2468 | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | Glucose-1-phosphate cytidylyltransferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR013446:IPR005835; KEGG: bfs:BF2603 putative LPS biosynthesis-related sugar-phosphate nucleotidyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate cytidylyltransferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase. | 0.995 |
| Lbys_2467 | Lbys_2469 | Lbys_2467 | Lbys_2469 | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: hmo:HM1_1228 glycosyl transferase, group 2 family protein, putative; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase, group 1/2 family protein; PFAM: Glycosyl transferase family 2. | 0.611 |
| Lbys_2467 | gmd | Lbys_2467 | Lbys_2464 | CDP-glucose 4,6-dehydratase; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR013445:IPR001509; KEGG: bfs:BF2602 putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: CDP-glucose-4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase. | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.703 |