STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_2500Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: coc:Coch_0582 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain. (208 aa)    
Predicted Functional Partners:
Lbys_0514
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: chu:CHU_2259 cyclic nucleotide binding regulatory protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding regulatory protein; PFAM: Cyclic nucleotide-binding domain.
  
     0.774
Lbys_2501
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: fps:FP0296 outer membrane efflux protein precursor; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein.
 
     0.611
Lbys_0949
InterPro IPR000595; KEGG: fjo:Fjoh_3733 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
     0.603
Lbys_2498
Exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: dfe:Dfer_4050 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ.
       0.561
Lbys_2499
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043; KEGG: chu:CHU_2469 [acyl-carrier-protein] S-malonyltransferase; PFAM: Acyl transferase; SPTR: [Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
       0.561
Lbys_2502
Biotin/lipoyl attachment domain-containing protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR000089; KEGG: fps:FP0295 ABC transporter membrane fusion efflux protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Secretion protein HlyD family protein; PFAM: HlyD family secretion protein.
       0.561
Lbys_2503
ABC-2 type transporter; COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: fps:FP0294 ABC transporter permease; PFAM: ABC-2 type transporter; SPTR: ABC family transporter permease protein; PFAM: ABC-2 type transporter.
  
    0.559
Lbys_1292
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467:IPR000014:IPR000700:IPR001610:I PR004358; KEGG: dfe:Dfer_5761 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; GAF domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; GAF domai [...]
  
 
 0.521
Lbys_2497
ABC transporter related protein; COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sli:Slin_1196 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
       0.500
Lbys_0503
COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 008207:IPR003018:IPR013767:IPR013655:IPR013656:IPR003661:I PR003594:IPR001610:IPR004358; KEGG: fba:FIC_01779 PAS/PAC domain protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containin [...]
  
 
 0.455
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.