STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_2637Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. (398 aa)    
Predicted Functional Partners:
Lbys_0057
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR018528:IPR010957:IPR020822:IPR001086:IPR 008242:IPR002701; KEGG: sli:Slin_2566 chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase, type II; SPTR: Chorismate mutase; TIGRFAM: chorismate mutase; PFAM: Prephenate dehydratase; Chorismate mutase type II; TIGRFAM: chorismate mutase domain of proteobacterial P-protein, clade 2.
 
 
 0.992
Lbys_1543
Glutamate synthase (NADH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: dfe:Dfer_5479 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
 
 0.946
Lbys_2279
COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518; KEGG: sli:Slin_0407 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase.
 
 0.935
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.925
Lbys_1576
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.923
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861:IPR001917:IPR004839; KEGG: dfe:Dfer_1138 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
0.919
Lbys_0607
Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: glo:Glov_2977 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
 
  
0.918
Lbys_0631
COGs: COG0527 Aspartokinase; InterProIPR018042:IPR019811:IPR011147:IPR001048:IPR 002912:IPR005106:IPR001342:IPR001341; KEGG: sli:Slin_4514 aspartate kinase; PFAM: homoserine dehydrogenase; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; PRIAM: Aspartate kinase., Homoserine dehydrogenase; SPTR: Aspartate kinase; TIGRFAM: aspartate kinase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase.
  
 0.918
Lbys_3137
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR015590:IPR005931; KEGG: sli:Slin_5523 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Belongs to the aldehyde dehydrogenase family.
   
 0.916
Lbys_1216
COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: yli:YALI0F17644g YALI0F17644p; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase (NADP(+)); SPTR: Prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
  
 
 0.915
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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