STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_2831KEGG: sli:Slin_1136 TonB-dependent receptor; SPTR: TonB-dependent receptor. (915 aa)    
Predicted Functional Partners:
Lbys_2832
Protein of unknown function, Porph ging; InterPro IPR019115; KEGG: sli:Slin_3442 hypothetical protein; PFAM: Protein of unknown function, Porph ging; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (Porph_ging).
 
     0.880
Lbys_2834
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cpi:Cpin_2742 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
     0.755
Lbys_2833
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: cpi:Cpin_0694 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
     0.750
Lbys_1588
KEGG: sli:Slin_0475 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3109).
  
     0.581
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.539
Lbys_2720
KEGG: sli:Slin_5701 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2795).
  
     0.514
Lbys_1195
TonB family protein; InterPro IPR008756:IPR006260; KEGG: sli:Slin_6187 TonB family protein; PFAM: peptidase M56 BlaR1; TonB domain; SPTR: Putative uncharacterized protein; TIGRFAM: TonB family protein; PFAM: BlaR1 peptidase M56; Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
 
   0.456
Lbys_3214
Outer membrane transport energization protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   0.454
Lbys_2263
RagB/SusD domain protein; InterPro IPR012944; KEGG: sli:Slin_4761 RagB/SusD domain protein; PFAM: RagB/SusD domain protein; SPTR: Putative uncharacterized protein; PFAM: SusD family.
  
 
   0.413
Lbys_3068
KEGG: dfe:Dfer_2695 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.409
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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