STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_3000COGs: COG0439 Biotin carboxylase; InterPro IPR003135:IPR011761; KEGG: dfe:Dfer_2846 ATP-dependent carboxylate-amine ligase domain-containing protein; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: ATP-dependent carboxylate-amine ligase domain-containing protein; PFAM: ATP-grasp domain. (399 aa)    
Predicted Functional Partners:
Lbys_1689
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.979
Lbys_2837
Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR002125:IPR002734:IPR004794:IPR016192; KEGG: sli:Slin_2937 riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthes [...]
   
   0.921
Lbys_1134
COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761; KEGG: fba:FIC_01388 glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase)-like protein; SPTR: Glutathione synthase/ribosomal protein S6 modification glutaminyl transferase-like protein.
 
   
 0.793
Lbys_1135
Putative esterase; COGs: COG4947 conserved hypothetical protein; KEGG: dfe:Dfer_0438 putative esterase; SPTR: Putative esterase; manually curated; PFAM: Putative esterase.
 
     0.782
Lbys_2999
KEGG: phe:Phep_1451 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Transcription elongation factor, GreA/GreB, C-term.
       0.782
Lbys_2306
Esterase; COGs: COG2819 hydrolase of the alpha/beta superfamily; InterPro IPR000801; KEGG: dfe:Dfer_4810 putative esterase; PFAM: esterase; SPTR: Putative esterase; PFAM: Putative esterase.
 
     0.781
Lbys_1132
COGs: COG0518 GMP synthase - Glutamine amidotransferase domain; InterPro IPR000991:IPR017926; KEGG: dfe:Dfer_0435 hypothetical protein; PFAM: glutamine amidotransferase class-I; SPTR: Putative uncharacterized protein; PFAM: Glutamine amidotransferase class-I.
  
  
 0.779
Lbys_1131
KEGG: dfe:Dfer_0434 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.775
Lbys_1751
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR004408; KEGG: sli:Slin_3003 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
 0.734
Lbys_1133
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
 
     0.678
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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