Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_3085COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600:IPR005829; KEGG: sli:Slin_1583 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family. (299 aa)    
Predicted Functional Partners:
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.915
Lbys_2169
COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR018322:IPR006148:IPR003737; KEGG: sli:Slin_5415 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; LmbE family protein; SPTR: Glucosamine-6-phosphate isomerase; TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; GlcNAc-PI de-N-acetylase; TIGRFAM: glucosamine-6-phosphate isomerase.
    
 0.915
xylA
COGs: COG2115 Xylose isomerase; InterPro IPR012307:IPR001998:IPR013452; KEGG: phe:Phep_1604 xylose isomerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Xylose isomerase; SPTR: Xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; Belongs to the xylose isomerase family.
    
 0.915
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: dfe:Dfer_1231 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
    
 0.915
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.908
Lbys_2840
KEGG: dfe:Dfer_3304 mannose-6-phosphate isomerase type II; SPTR: Mannose-6-phosphate isomerase type II; PFAM: Mannose-6-phosphate isomerase.
    
 0.904
fbp
D-fructose 1,6-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR020548; KEGG: zpr:ZPR_0468 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: Fructose-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase.
     
  0.900
Lbys_2514
Glycoside hydrolase 97; InterPro IPR019563; KEGG: rmr:Rmar_0476 alpha-glucosidase, putative, adg97A; PFAM: Glycoside hydrolase 97; SPTR: Alpha-glucosidase, putative, adg97A; PFAM: Glycoside hydrolase 97.
     
  0.900
Lbys_2253
COGs: COG4124 Beta-mannanase; InterPro IPR000805; KEGG: gym:GYMC10_1236 mannan endo-1,4-beta-mannosidase; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: Mannan endo-1,4-beta-mannosidase; PFAM: Glycosyl hydrolase family 26; Belongs to the glycosyl hydrolase 26 family.
   
 
  0.828
Lbys_3427
COGs: COG4124 Beta-mannanase; InterPro IPR000805:IPR016714; KEGG: fjo:Fjoh_4953 glycoside hydrolase family protein; PRIAM: Mannan endo-1,4-beta-mannosidase; SPTR: Mannase; PFAM: Glycosyl hydrolase family 26; Belongs to the glycosyl hydrolase 26 family.
   
 
  0.828
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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