STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_3104Thioesterase superfamily protein; COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR006683:IPR003736; KEGG: sli:Slin_2909 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: Thioesterase superfamily protein; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1. (137 aa)    
Predicted Functional Partners:
menB
1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
  
 0.961
menA
1,4-dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
  
 0.933
Lbys_3103
Patatin; COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: sli:Slin_3007 patatin; PFAM: Patatin; SPTR: Patatin; PFAM: Patatin-like phospholipase.
       0.773
Lbys_3105
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078:IPR001345; KEGG: sli:Slin_2908 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
       0.621
menD-2
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.607
Lbys_3102
InterPro IPR002591; KEGG: sli:Slin_3004 type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; SPTR: Type I phosphodiesterase/nucleotide pyrophosphatase; PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase.
       0.603
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene -1-carboxylic-acidsynthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.557
plsX
Phosphate:acyl-(acyl carrier protein) acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.496
Lbys_1329
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: sli:Slin_1750 O-succinylbenzoic acid--CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: O-succinylbenzoic acid--CoA ligase; PFAM: AMP-binding enzyme.
 
   
 0.461
Lbys_0747
Chorismate binding protein; COGs: COG1169 Isochorismate synthase; InterPro IPR015890; KEGG: sli:Slin_0770 chorismate binding-like protein; PFAM: Chorismate binding-like; SPTR: Chorismate binding-like protein; PFAM: chorismate binding enzyme.
 
  
 0.459
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
Server load: low (30%) [HD]