STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lbys_3185Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)    
Predicted Functional Partners:
Lbys_1116
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: chu:CHU_2468 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase); PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inediphosphokinase(7,8-dihydro-6-hydroxymethylpterin-pyrop hosphokinase); TIGRFAM:2-amino-4-hydroxy-6-hydrox [...]
 
 
 0.998
Lbys_1609
COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR006390; KEGG: fjo:Fjoh_3497 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Putative dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
 
 0.998
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR001474:IPR018234:IPR020602; KEGG: chu:CHU_0955 GTP cyclohydrolase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
 
  
 0.982
Lbys_2088
COGs: COG1785 Alkaline phosphatase; InterPro IPR001952:IPR006311; KEGG: fjo:Fjoh_3187 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase; PFAM: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Lbys_3186
DivIVA domain; InterPro IPR007793:IPR019933; KEGG: sli:Slin_5835 DivIVA domain protein; PFAM: DivIVA family protein; SPTR: DivIVA domain protein; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain.
 
     0.836
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
 0.831
Lbys_3182
Thioesterase superfamily protein; COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: fba:FIC_01188 cytosolic long-chain acyl-CoA thioester hydrolase family protein; PFAM: thioesterase superfamily protein; SPTR: 4-hydroxybenzoyl-CoA thioesterase domain protein; PFAM: Thioesterase superfamily.
  
    0.795
Lbys_3184
Major facilitator superfamily MFS_1; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dfe:Dfer_3286 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; manually curated; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily; TIGRFAM: Multidrug resistance protein.
       0.773
Lbys_0928
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR018109:IPR013221; KEGG: dfe:Dfer_1048 FolC bifunctional protein; PFAM: Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: Folylpolyglutamate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
 
  
 0.655
Lbys_3187
WD40 repeat, subgroup; InterProIPR001680:IPR019782:IPR017986:IPR019775:IPR 020472:IPR019781; KEGG: chu:CHU_0759 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD-40 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: WD domain, G-beta repeat.
       0.601
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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