| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lbys_0059 | Lbys_3395 | Lbys_0059 | Lbys_3395 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.539 |
| Lbys_0059 | coaD | Lbys_0059 | Lbys_3262 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.774 |
| Lbys_0059 | coaE | Lbys_0059 | Lbys_0024 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.609 |
| Lbys_0059 | gmk | Lbys_0059 | Lbys_1680 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.577 |
| Lbys_0059 | guaA | Lbys_0059 | Lbys_1213 | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.528 |
| Lbys_1022 | Lbys_3395 | Lbys_1022 | Lbys_3395 | Protein of unknown function DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF479. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
| Lbys_1022 | coaD | Lbys_1022 | Lbys_3262 | Protein of unknown function DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF479. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.901 |
| Lbys_1022 | coaX | Lbys_1022 | Lbys_1442 | Protein of unknown function DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF479. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.900 |
| Lbys_1022 | coaX-2 | Lbys_1022 | Lbys_1682 | Protein of unknown function DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF479. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.900 |
| Lbys_3260 | Lbys_3261 | Lbys_3260 | Lbys_3261 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: sli:Slin_5938 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: sli:Slin_5939 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR. | 0.990 |
| Lbys_3260 | coaD | Lbys_3260 | Lbys_3262 | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: sli:Slin_5938 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.773 |
| Lbys_3261 | Lbys_3260 | Lbys_3261 | Lbys_3260 | COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: sli:Slin_5939 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR. | MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: sli:Slin_5938 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family. | 0.990 |
| Lbys_3261 | coaD | Lbys_3261 | Lbys_3262 | COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: sli:Slin_5939 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.778 |
| Lbys_3395 | Lbys_0059 | Lbys_3395 | Lbys_0059 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; COGs: COG0196 FAD synthase; InterPro IPR004821:IPR002606:IPR015864:IPR015865; KEGG: sli:Slin_0790 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; cytidyltransferase-related domain protein; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain; Belongs to the ribF family. | 0.539 |
| Lbys_3395 | Lbys_1022 | Lbys_3395 | Lbys_1022 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Protein of unknown function DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF479. | 0.900 |
| Lbys_3395 | coaD | Lbys_3395 | Lbys_3262 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.941 |
| Lbys_3395 | coaE | Lbys_3395 | Lbys_0024 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.539 |
| Lbys_3395 | coaX | Lbys_3395 | Lbys_1442 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.929 |
| Lbys_3395 | coaX-2 | Lbys_3395 | Lbys_1682 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.927 |
| Lbys_3395 | gmk | Lbys_3395 | Lbys_1680 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.634 |