Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Lbys_3397Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR020904:IPR002347:IPR002198; KEGG: dfe:Dfer_3922 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)    
Predicted Functional Partners:
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
      0.900
Lbys_3398
FAD linked oxidase domain protein; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR017896:IPR016166:IPR017900:IPR006094:IPR 004113; KEGG: phe:Phep_3343 D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; SPTR: D-lactate dehydrogenase (Cytochrome); PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain.
 
    0.827
Lbys_3395
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
       0.603
Lbys_3396
KEGG: dfe:Dfer_5211 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.603
gcvP
Glycine dehydrogenase (decarboxylating) beta subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
      0.557
Lbys_0192
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: cpi:Cpin_0127 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
 
    0.463
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.451
Lbys_3394
FAD dependent oxidoreductase; COGs: COG0579 dehydrogenase; InterPro IPR006076; KEGG: dfe:Dfer_3598 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase.
       0.429
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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