| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lbys_0242 | Lbys_2637 | Lbys_0242 | Lbys_2637 | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | 0.910 |
| Lbys_0242 | Lbys_3501 | Lbys_0242 | Lbys_3501 | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.699 |
| Lbys_0242 | Lbys_3502 | Lbys_0242 | Lbys_3502 | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR005708; KEGG: fjo:Fjoh_0728 homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase; SPTR: Homogentisate 1,2-dioxygenase; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase. | 0.912 |
| Lbys_0242 | hisC | Lbys_0242 | Lbys_0732 | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861:IPR001917:IPR004839; KEGG: dfe:Dfer_1138 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.916 |
| Lbys_1777 | Lbys_2637 | Lbys_1777 | Lbys_2637 | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dfe:Dfer_4274 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | 0.902 |
| Lbys_1777 | Lbys_3501 | Lbys_1777 | Lbys_3501 | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dfe:Dfer_4274 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.907 |
| Lbys_1777 | hisC | Lbys_1777 | Lbys_0732 | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dfe:Dfer_4274 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861:IPR001917:IPR004839; KEGG: dfe:Dfer_1138 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.902 |
| Lbys_1917 | Lbys_3501 | Lbys_1917 | Lbys_3501 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: phe:Phep_0639 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase beta chain; PFAM: Carboxyl transferase domain. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.522 |
| Lbys_2637 | Lbys_0242 | Lbys_2637 | Lbys_0242 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | 0.910 |
| Lbys_2637 | Lbys_1777 | Lbys_2637 | Lbys_1777 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dfe:Dfer_4274 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. | 0.902 |
| Lbys_2637 | Lbys_3501 | Lbys_2637 | Lbys_3501 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.907 |
| Lbys_2637 | hisC | Lbys_2637 | Lbys_0732 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR001176:IPR004839; KEGG: dfe:Dfer_3724 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861:IPR001917:IPR004839; KEGG: dfe:Dfer_1138 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.920 |
| Lbys_2970 | Lbys_3501 | Lbys_2970 | Lbys_3501 | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: sli:Slin_4899 methylcrotonoyl-CoA carboxylase; PFAM: carboxyl transferase; PRIAM: Methylcrotonoyl-CoA carboxylase; SPTR: Methylcrotonoyl-CoA carboxylase; PFAM: Carboxyl transferase domain. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.522 |
| Lbys_3500 | Lbys_3501 | Lbys_3500 | Lbys_3501 | Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sli:Slin_0337 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | 0.548 |
| Lbys_3500 | Lbys_3502 | Lbys_3500 | Lbys_3502 | Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sli:Slin_0337 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. | COGs: COG3508 Homogentisate 1 2-dioxygenase; InterPro IPR005708; KEGG: fjo:Fjoh_0728 homogentisate 1,2-dioxygenase; PFAM: homogentisate 12-dioxygenase; SPTR: Homogentisate 1,2-dioxygenase; PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase. | 0.548 |
| Lbys_3500 | Lbys_3503 | Lbys_3500 | Lbys_3503 | Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sli:Slin_0337 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. | Fumarylacetoacetase; COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR015377:IPR002529:IPR005959; KEGG: gfo:GFO_2263 fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969; PRIAM: Fumarylacetoacetase; SPTR: Fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase. | 0.548 |
| Lbys_3500 | Lbys_3504 | Lbys_3500 | Lbys_3504 | Transcriptional regulator, LysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sli:Slin_0337 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: Transcriptional regulator, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain. | COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: cpi:Cpin_0500 flavin reductase domain protein FMN-binding; PFAM: flavin reductase domain protein FMN-binding; SPTR: Nitrilotriacetate monooxygenase component B; PFAM: Flavin reductase like domain. | 0.548 |
| Lbys_3501 | Lbys_0242 | Lbys_3501 | Lbys_0242 | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | Aromatic amino acid hydroxylase; COGs: COG3186 Phenylalanine-4-hydroxylase; InterPro IPR019774; KEGG: phe:Phep_3273 phenylalanine 4-monooxygenase; PFAM: Aromatic amino acid hydroxylase-like; SPTR: Phenylalanine-4-hydroxylase; PFAM: Biopterin-dependent aromatic amino acid hydroxylase. | 0.699 |
| Lbys_3501 | Lbys_1777 | Lbys_3501 | Lbys_1777 | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: dfe:Dfer_4274 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase. | 0.907 |
| Lbys_3501 | Lbys_1917 | Lbys_3501 | Lbys_1917 | COGs: COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins; InterPro IPR004360:IPR005956; KEGG: cpi:Cpin_5420 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; PRIAM: 4-hydroxyphenylpyruvate dioxygenase; SPTR: 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase. | COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022:IPR011762:IPR011763; KEGG: phe:Phep_0639 carboxyl transferase; PFAM: carboxyl transferase; SPTR: Propionyl-CoA carboxylase beta chain; PFAM: Carboxyl transferase domain. | 0.522 |