Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lbys_3603Heavy metal efflux pump, CzcA family; COGs: COG3696 Putative silver efflux pump; InterPro IPR001036:IPR004763; KEGG: fjo:Fjoh_4462 CzcA family heavy metal efflux protein; PFAM: acriflavin resistance protein; SPTR: Possible RND superfamily resistance-nodulation-cell division [ligand]:proton (H+) antiporter; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: Outer membrane efflux protein; AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1417 aa)    
Predicted Functional Partners:
Lbys_3602
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: fps:FP0881 membrane fusion efflux protein precursor; SPTR: Membrane fusion efflux protein; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.963
Lbys_3599
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dfe:Dfer_1589 efflux transporter, RND family, MFP subunit; SPTR: RND family efflux transporter MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.926
Lbys_2084
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: fjo:Fjoh_4294 RND family efflux transporter MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.807
Lbys_3601
KEGG: fjo:Fjoh_3348 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
       0.646
Lbys_3600
Heavy metal efflux pump, CzcA family; COGs: COG3696 Putative silver efflux pump; InterPro IPR001036:IPR004763; KEGG: dfe:Dfer_1588 heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; SPTR: Heavy metal efflux pump, CzcA family; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: AcrB/AcrD/AcrF family; Outer membrane efflux protein; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
0.628
Lbys_1103
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: sli:Slin_0257 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: RND family efflux transporter, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.625
Lbys_3604
KEGG: fjo:Fjoh_3934 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.605
Lbys_2688
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dfe:Dfer_1001 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.564
Lbys_3122
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: phe:Phep_3707 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.553
Lbys_1229
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dfe:Dfer_3208 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.496
Your Current Organism:
Leadbetterella byssophila
NCBI taxonomy Id: 649349
Other names: L. byssophila DSM 17132, Leadbetterella byssophila 4M15, Leadbetterella byssophila DSM 17132, Leadbetterella byssophila str. DSM 17132, Leadbetterella byssophila strain DSM 17132
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