node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Trad_0026 | Trad_0027 | Trad_0026 | Trad_0027 | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.779 |
Trad_0026 | Trad_0029 | Trad_0026 | Trad_0029 | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | 0.536 |
Trad_0026 | nadD | Trad_0026 | Trad_0025 | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.963 |
Trad_0026 | obg | Trad_0026 | Trad_0024 | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.772 |
Trad_0026 | rsfS | Trad_0026 | Trad_0028 | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.861 |
Trad_0027 | Trad_0026 | Trad_0027 | Trad_0026 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | 0.779 |
Trad_0027 | Trad_0029 | Trad_0027 | Trad_0029 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | 0.681 |
Trad_0027 | Trad_0434 | Trad_0027 | Trad_0434 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.662 |
Trad_0027 | Trad_0683 | Trad_0027 | Trad_0683 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Glycosyl transferase, family 4, conserved region; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480:IPR018481; KEGG: dge:Dgeo_1295 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Q1IYU3 Glycosyl transferase, family 4; PFAM: Glycosyl transferase family 4. | 0.767 |
Trad_0027 | Trad_1378 | Trad_0027 | Trad_1378 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Glycosyl transferase, WecB/TagA/CpsF family; COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: dau:Daud_2098 WecB/TagA/CpsF family glycosyl transferase; PFAM: glycosyl transferase WecB/TagA/CpsF; PRIAM: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; SPTR: C1XQG0 N-acetylmannosaminyltransferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family. | 0.732 |
Trad_0027 | Trad_1641 | Trad_0027 | Trad_1641 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | COGs: COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; KEGG: ttj:TTHA1786 hypothetical protein; SPTR: C1XGV5 Putative uncharacterized protein; PFAM: Predicted periplasmic protein (DUF2233). | 0.683 |
Trad_0027 | Trad_1957 | Trad_0027 | Trad_1957 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Polysaccharide pyruvyl transferase CsaB; COGs: COG2327 conserved hypothetical protein; InterPro IPR019896:IPR007345; KEGG: ttj:TTHA0576 putative pyruvyl-transferase; PFAM: polysaccharide pyruvyl transferase; SPTR: Q5SKR7 Putative pyruvyl-transferase; TIGRFAM: polysaccharide pyruvyl transferase CsaB; manually curated; PFAM: Polysaccharide pyruvyl transferase; TIGRFAM: polysaccharide pyruvyl transferase CsaB. | 0.780 |
Trad_0027 | nadD | Trad_0027 | Trad_0025 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.676 |
Trad_0027 | obg | Trad_0027 | Trad_0024 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.636 |
Trad_0027 | rsfS | Trad_0027 | Trad_0028 | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.761 |
Trad_0029 | Trad_0026 | Trad_0029 | Trad_0026 | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | Metal dependent phosphohydrolase; COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006674:IPR003607; KEGG: tth:TTC1420 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C1XI98 Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488. | 0.536 |
Trad_0029 | Trad_0027 | Trad_0029 | Trad_0027 | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: dra:DR_2581 LytR/CspA/Psr family protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: C1XI97 Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. | 0.681 |
Trad_0029 | nadD | Trad_0029 | Trad_0025 | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.554 |
Trad_0029 | obg | Trad_0029 | Trad_0024 | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.519 |
Trad_0029 | rsfS | Trad_0029 | Trad_0028 | Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: ttj:TTHA0372 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: B7A9I8 Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.783 |