STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_0303COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR015424:IPR015421; KEGG: ddr:Deide_09840 putative aminotransferase class-V; PFAM: aminotransferase class V; SPTR: C1CUJ8 Putative Aminotransferase class-V; PFAM: Aminotransferase class-V. (378 aa)    
Predicted Functional Partners:
Trad_0302
COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterProIPR006236:IPR006139:IPR006140:IPR002912:IPR 016040; KEGG: ttj:TTHA0952 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; SPTR: B7A719 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic d [...]
 
  
 0.882
Trad_0304
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tth:TT_P0020 hypothetical protein; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Q746N3 Hypothetical conserved protein; manually curated; PFAM: HEPN domain.
       0.773
Trad_0305
KEGG: ttj:TTHB064 hypothetical protein; SPTR: Q746N2 Hypothetical conserved protein; manually curated; PFAM: Nucleotidyltransferase domain.
       0.773
Trad_0306
KEGG: aeh:Mlg_1165 hypothetical protein; SPTR: Q1K2R9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2721).
       0.727
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.550
purD
COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR011761:IPR020562:IPR020561:IPR020560:IPR 013817:IPR013815:IPR013816:IPR020559:IPR016185:IPR011054:I PR000115; KEGG: tth:TTC0460 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Q72KQ8 Phosphoribosylamine-glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribos [...]
  
    0.541
Trad_0209
COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932:IPR000583:IPR006982:IPR002932:IPR 002489:IPR013785; KEGG: chl:Chy400_3517 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: B9LCZ9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.520
Trad_0301
KEGG: sus:Acid_3738 hypothetical protein; SPTR: Q01NA9 Putative uncharacterized protein.
       0.473
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 0.448
Trad_2342
COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR013785:IPR000262; KEGG: adg:Adeg_1075 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: C9RD75 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent dehydrogenase.
  
 0.448
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.