STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Trad_0395Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: vap:Vapar_5244 aminotransferase class IV; PFAM: aminotransferase class IV; SPTR: A0Z4Z3 Branched-chain amino acid aminotransferase, putative; PFAM: Aminotransferase class IV; TIGRFAM: D-amino acid aminotransferase; branched-chain amino acid aminotransferase, group I. (310 aa)    
Predicted Functional Partners:
Trad_0396
KEGG: GSVIVT00022872001; hypothetical protein LOC100264940; SPTR: D0DA48 Branched chain amino acid aminotransferase.
     0.994
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404:IPR020558:IPR000581; KEGG: dge:Dgeo_1240 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Q1IYZ8 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.968
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 0.959
Trad_0208
2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterProIPR000891:IPR005675:IPR013709:IPR013785:IPR 002034; KEGG: tth:TTC0847 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; SPTR: Q72JD1 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family prote [...]
 
 0.953
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.924
Trad_0747
Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476:IPR015941:IPR009014; KEGG: ttj:TTHA0230 2-oxoisovalerate dehydrogenase, E1 component beta subunit; PFAM: Transketolase central region; Transketolase domain protein; SPTR: C1XX73 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
 0.918
Trad_1960
COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR015424:IPR015421:IPR005814; KEGG: sus:Acid_7662 aminotransferase; PFAM: aminotransferase class-III; SPTR: Q01P59 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.916
Trad_0086
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
   
 0.914
Trad_0746
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017; KEGG: tth:TTC1757 2-oxoisovalerate dehydrogenase alpha subunit; PFAM: dehydrogenase E1 component; PRIAM: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); SPTR: B7A915 Pyruvate dehydrogenase (Acetyl-transferring); PFAM: Dehydrogenase E1 component.
  
 
 0.908
Trad_2552
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR019811:IPR016040; KEGG: ttj:TTHA0489 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: C1XW41 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain.
  
 
 0.872
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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