node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Trad_0863 | Trad_0891 | Trad_0863 | Trad_0891 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | InterPro IPR000537; KEGG: dge:Dgeo_2470 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Q1J3N0 UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | 0.914 |
Trad_0863 | Trad_2224 | Trad_0863 | Trad_2224 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.979 |
Trad_0863 | mqnA | Trad_0863 | Trad_0909 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.773 |
Trad_0863 | mqnD | Trad_0863 | Trad_1214 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.676 |
Trad_0863 | mqnE | Trad_0863 | Trad_0908 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.669 |
Trad_0863 | ubiX | Trad_0863 | Trad_0982 | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.992 |
Trad_0891 | Trad_0863 | Trad_0891 | Trad_0863 | InterPro IPR000537; KEGG: dge:Dgeo_2470 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Q1J3N0 UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 0.914 |
Trad_0891 | Trad_2224 | Trad_0891 | Trad_2224 | InterPro IPR000537; KEGG: dge:Dgeo_2470 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Q1J3N0 UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 0.900 |
Trad_0891 | ubiX | Trad_0891 | Trad_0982 | InterPro IPR000537; KEGG: dge:Dgeo_2470 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Q1J3N0 UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.914 |
Trad_0981 | ispD | Trad_0981 | Trad_0983 | Hypothetical protein; KEGG: bbt:BBta_0983 major facilitator superfamily permease; SPTR: B5G9J7 Predicted protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.481 |
Trad_0981 | ispE | Trad_0981 | Trad_0984 | Hypothetical protein; KEGG: bbt:BBta_0983 major facilitator superfamily permease; SPTR: B5G9J7 Predicted protein. | 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.481 |
Trad_0981 | ubiX | Trad_0981 | Trad_0982 | Hypothetical protein; KEGG: bbt:BBta_0983 major facilitator superfamily permease; SPTR: B5G9J7 Predicted protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.481 |
Trad_2224 | Trad_0863 | Trad_2224 | Trad_0863 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | UbiD family decarboxylase; COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: dra:DR_0332 hypothetical protein; PFAM: Carboxylyase-related protein; SPTR: Q9RXI1 Putative uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family. | 0.979 |
Trad_2224 | Trad_0891 | Trad_2224 | Trad_0891 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | InterPro IPR000537; KEGG: dge:Dgeo_2470 UbiA prenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Q1J3N0 UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | 0.900 |
Trad_2224 | mqnA | Trad_2224 | Trad_0909 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.800 |
Trad_2224 | mqnD | Trad_2224 | Trad_1214 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.791 |
Trad_2224 | mqnE | Trad_2224 | Trad_0908 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.792 |
Trad_2224 | ubiX | Trad_2224 | Trad_0982 | COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371:IPR018483; KEGG: ttj:TTHA0605 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: C1XND1 4-hydroxybenzoate octaprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.972 |
ispD | Trad_0981 | Trad_0983 | Trad_0981 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | Hypothetical protein; KEGG: bbt:BBta_0983 major facilitator superfamily permease; SPTR: B5G9J7 Predicted protein. | 0.481 |
ispD | ispE | Trad_0983 | Trad_0984 | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.997 |