STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_1396Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR011059; KEGG: sti:Sthe_0262 amidohydrolase; PFAM: amidohydrolase; SPTR: D1C6U0 Amidohydrolase; PFAM: Amidohydrolase family. (480 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
   
  0.909
Trad_2198
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.903
Trad_0151
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: ttj:TTHA0872 amidohydrolase family protein; PFAM: amidohydrolase; SPTR: C1XT71 Cytosine deaminase-like metal-dependent hydrolase; PFAM: Amidohydrolase family.
  
     0.754
lysY
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
  
    0.520
Trad_1401
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814:IPR004636:IPR015421:IPR015424; KEGG: ttj:TTHA1755 acetylornithine/acetyl-lysine aminotransferase; PFAM: aminotransferase class-III; SPTR: B7A5Y2 Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases.
     
 0.509
lysZ
Acetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily.
  
    0.507
Trad_1397
InterPro IPR002145; KEGG: mbt:JTY_2567 hypothetical protein; PFAM: CopG domain protein DNA-binding domain protein; SPTR: A8UV44 Putative uncharacterized protein; PFAM: Ribbon-helix-helix protein, copG family.
       0.505
vapC-4
PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.505
Trad_1400
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR000086:IPR020476:IPR015797; KEGG: ttr:Tter_2108 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D1CGY9 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
       0.505
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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