STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_1711Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006158:IPR006159; KEGG: ttj:TTHA1038 methylmalonyl-CoA mutase, alpha subunit, chain B; PFAM: cobalamin B12-binding domain protein; SPTR: Q72JU2 Methylmalonyl-CoA mutase small subunit; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain. (138 aa)    
Predicted Functional Partners:
Trad_0513
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR016176:IPR014348:IPR006098; KEGG: ttj:TTHA1246 methylmalonyl-CoA mutase; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C1XUL4 Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain.
 0.999
Trad_1710
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR014348:IPR016176:IPR006098; KEGG: dge:Dgeo_0862 methylmalonyl-CoA mutase, alpha subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: Q1J020 Methylmalonyl-CoA mutase, alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain.
 0.999
Trad_1762
methylmalonyl-CoA epimerase; InterPro IPR004360:IPR017515; KEGG: dge:Dgeo_1790 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Q1IXE9 Glyoxalase/bleomycin resistance protein/dioxygenase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
  
 0.998
Trad_0553
LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129:IPR003593; KEGG: ttj:TTHA0136 LAO/AO transport system kinase; PFAM: ArgK protein; SMART: AAA ATPase; SPTR: Q5SM07 LAO/AO transport system kinase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase.
  
 0.988
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.923
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.918
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.832
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
    
 0.832
Trad_0742
2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterProIPR011278:IPR019810:IPR002020:IPR016142:IPR 016141; KEGG: bha:BH3160 citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Q9K847 Citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
     
 0.826
Trad_0748
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089:IPR003016:IPR004167:IPR001078:IPR 011053; KEGG: tth:TTC1754 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: C1XX74 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogena [...]
  
 
 0.807
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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