STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_1817COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: dge:Dgeo_2262 DNA polymerase III subunit, putative; SPTR: C1XJM6 Putative uncharacterized protein. (313 aa)    
Predicted Functional Partners:
Trad_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.999
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
0.996
Trad_0552
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR008921:IPR005790; KEGG: dge:Dgeo_0745 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: Q1J0D7 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III subunits gamma and tau domain III; DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 
 0.994
Trad_2353
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR006142:IPR016195:IPR003141:IPR003587:IPR 003586:IPR004013:IPR011708:IPR004365:IPR004805:IPR006141:I PR004042; KEGG: ttj:TTHA0180 DNA polymerase III alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; Hedgehog/intein hint domain protein; SPTR: B7ABG0 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP [...]
    
 0.994
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.964
Trad_0247
COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520:IPR012337:IPR006055; KEGG: cef:CE1385 putative DNA polymerase III epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: C5SA67 Exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease.
   
 0.921
Trad_1522
COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520:IPR006055:IPR012337; KEGG: hch:HCH_00401 putative exonuclease; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; SPTR: Q2SPW2 Putative exonuclease; PFAM: Exonuclease.
   
 0.921
Trad_0598
Type III restriction protein res subunit; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR006935:IPR014013:IPR001650:IPR006555; KEGG: mth:MTH1347 ATP-dependent helicase; PFAM: type III restriction protein res subunit; SMART: helicase c2; SPTR: O27401 Probable ATP-dependent helicase; PFAM: Type III restriction enzyme, res subunit; DEAD_2.
  
 0.841
Trad_1816
Metallophosphoesterase; InterPro IPR004843:IPR011152; KEGG: dra:DR_2331 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Q9RRZ8 Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
       0.837
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.784
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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