STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_1872Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR016040:IPR002347:IPR002198; KEGG: ttj:TTHA0461 dihydropteridine/dihydrofolate reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XV89 Dihydropteridine reductase; PFAM: short chain dehydrogenase. (236 aa)    
Predicted Functional Partners:
Trad_2795
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.933
Trad_0313
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114:IPR010084; KEGG: ttj:TTHA1815 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: C7IF99 Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabZ; TIGRFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ.
  
 0.925
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.909
fabH-2
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.909
Trad_1871
NUDIX hydrolase; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR015797:IPR000086:IPR020476:IPR020084; KEGG: syn:sll1537 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: C1XV90 ADP-ribose pyrophosphatase; PFAM: NUDIX domain.
 
     0.856
Trad_1783
Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002347:IPR002198:IPR016040; KEGG: ttj:TTHA0394 short chain dehydrogenase/reductase family oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XHX5 Short-chain alcohol dehydrogenase; PFAM: short chain dehydrogenase.
 
    0.754
Trad_1873
COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016303:IPR002658; KEGG: dge:Dgeo_2474 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: Q1J3M6 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase.
     
 0.588
Trad_1874
KEGG: hau:Haur_1554 hypothetical protein; SPTR: A9B4N2 Putative uncharacterized protein.
       0.588
Trad_1875
TatD-related deoxyribonuclease; COGs: COG1099 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR012022:IPR001130; KEGG: dge:Dgeo_2472 TatD-related deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: Q1J3M8 TatD-related deoxyribonuclease; PFAM: TatD related DNase.
       0.572
Trad_1081
COGs: COG0404 Glycine cleavage system T protein (aminomethyltransferase); InterPro IPR006223:IPR006222:IPR013977; KEGG: dge:Dgeo_1905 glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; SPTR: C1XJS7 Aminomethyltransferase; TIGRFAM: glycine cleavage system T protein; PFAM: Aminomethyltransferase folate-binding domain; Glycine cleavage T-protein C-terminal barrel domain; TIGRFAM: sarcosine oxidase, gamma subunit family, heterotetrameric form; glycine cleavage system T protein.
   
 0.535
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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