Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Score
Trad_2000Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR016040:IPR002347:IPR002198; KEGG: cyc:PCC7424_0442 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B4B477 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase. (252 aa)    
Predicted Functional Partners:
Trad_2936
Hydroxymethylglutaryl-CoA lyase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR013785:IPR000891; KEGG: ttj:TTHA1526 hydroxymethylglutaryl-CoA lyase like protein; PFAM: pyruvate carboxyltransferase; PRIAM: Hydroxymethylglutaryl-CoA lyase; SPTR: C1XQB7 Hydroxymethylglutaryl-CoA lyase; PFAM: HMGL-like.
  
 
  0.923
Trad_0614
acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR005914:IPR020845:IPR000873; KEGG: aeh:Mlg_2108 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: Q0A6T7 Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase.
   
  0.902
Trad_1783
Short-chain dehydrogenase/reductase SDR; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002347:IPR002198:IPR016040; KEGG: ttj:TTHA0394 short chain dehydrogenase/reductase family oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XHX5 Short-chain alcohol dehydrogenase; PFAM: short chain dehydrogenase.
 
    0.586
Trad_2002
N-carbamoylputrescine amidase; COGs: COG0388 amidohydrolase; InterPro IPR017755:IPR003010; KEGG: ddr:Deide_22900 putative hydrolase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: C1XPI7 N-carbamoylputrescine amidase; TIGRFAM: N-carbamoylputrescine amidase; PFAM: Carbon-nitrogen hydrolase; TIGRFAM: N-carbamoylputrescine amidase.
   
   0.559
Trad_2001
Agmatine deiminase; COGs: COG2957 Peptidylarginine deiminase; InterPro IPR007466; KEGG: ddr:Deide_22800 putative agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; PRIAM: Agmatine deiminase; SPTR: C1XPI8 Peptidylarginine deiminase-like enzyme; PFAM: Porphyromonas-type peptidyl-arginine deiminase; Belongs to the agmatine deiminase family.
  
    0.545
Trad_0199
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347:IPR016040; KEGG: ttj:TTHB094 putative short-chain oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: C1XIG3 Putative uncharacterized protein; PFAM: short chain dehydrogenase.
  
 
   0.519
Trad_2250
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347:IPR002198:IPR016040; KEGG: mno:Mnod_7667 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B8IQV2 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
   0.438
Trad_1898
Phenylacetic acid degradation protein paaN; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR011966:IPR016161:IPR016162:IPR015590:IPR 002539; KEGG: dge:Dgeo_1913 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; SPTR: C1XT04 Phenylacetic acid degradation protein paaN; TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC like domain; Aldehyde dehydrogenase family; TIGRFAM: phenylacetic acid degradation protein paaN.
  
 0.437
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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