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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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nfoApurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (292 aa)    
Predicted Functional Partners:
Trad_2140
KEGG: hypothetical protein LOC769731; SPTR: B1Z9G0 Putative uncharacterized protein.
       0.773
Trad_2274
Glycoside hydrolase 15-related protein; COGs: COG3387 Glucoamylase and related glycosyl hydrolase; InterPro IPR008928:IPR012341:IPR011613; KEGG: ttr:Tter_2035 glycoside hydrolase 15-related protein; PFAM: glycoside hydrolase 15-related; SPTR: B5H854 Glycoside hydrolase; PFAM: Glycosyl hydrolases family 15.
 
     0.667
Trad_2232
Conserved hypothetical protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dra:DR_0462 hypothetical protein; SPTR: Q9RX53 Putative uncharacterized protein; PFAM: Periplasmic binding protein.
 
      0.650
Trad_2138
NADH:flavin oxidoreductase/NADH oxidase; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR013785:IPR001155; KEGG: psa:PST_2757 FMN oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: A4VN56 Probable FMN oxidoreductase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family.
  
  
 0.647
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.585
Trad_2905
HhH-GPD family protein; COGs: COG0177 EndoIII-related endonuclease; InterPro IPR003265:IPR003651:IPR011257; KEGG: hau:Haur_4286 HhH-GPD family protein; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; SMART: HhH-GPD family protein; SPTR: A9AY36 HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein.
  
 
 0.585
Trad_2137
COGs: COG2124 Cytochrome P450; InterPro IPR002397:IPR001128:IPR017972; KEGG: swi:Swit_3367 cytochrome P450-like protein; PFAM: cytochrome P450; SPTR: A5VBP7 Cytochrome P450-like protein; PFAM: Cytochrome P450.
       0.536
Trad_1917
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.516
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.478
Trad_0048
DNA-3-methyladenine glycosylase II; COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR011257; KEGG: mac:MA3207 DNA-3-methyladenine glycosylase II; SPTR: Q8TL35 DNA-3-methyladenine glycosylase II.
   
 
 0.467
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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