node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Trad_0086 | Trad_0904 | Trad_0086 | Trad_0904 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | 0.930 |
Trad_0086 | Trad_1243 | Trad_0086 | Trad_1243 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | 0.907 |
Trad_0086 | Trad_1866 | Trad_0086 | Trad_1866 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR015424:IPR015421:IPR001176:IPR004839; KEGG: kol:Kole_0146 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: C1XVE0 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II. | 0.942 |
Trad_0086 | Trad_1868 | Trad_0086 | Trad_1868 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Transferase hexapeptide repeat containing protein; COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451; KEGG: gsu:GSU1960 hexapeptide transferase family protein; PFAM: transferase hexapeptide repeat containing protein; SPTR: Q74BU4 Hexapeptide transferase family protein; PFAM: Bacterial transferase hexapeptide (three repeats). | 0.403 |
Trad_0086 | Trad_2278 | Trad_0086 | Trad_2278 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Cysteine synthase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR015424:IPR015421:IPR015422:IPR000277; KEGG: cpc:Cpar_0621 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: Q8KES8 O-acetylhomoserine (Thiol)-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.935 |
Trad_0086 | Trad_2279 | Trad_0086 | Trad_2279 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterProIPR015424:IPR015421:IPR015422:IPR000277:IPR 006235; KEGG: dge:Dgeo_0518 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Q1J114 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | 0.936 |
Trad_0086 | Trad_2519 | Trad_0086 | Trad_2519 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
Trad_0086 | Trad_2797 | Trad_0086 | Trad_2797 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR005856:IPR005859:IPR001926; KEGG: dge:Dgeo_1657 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Q1IXT2 Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.981 |
Trad_0086 | metXA | Trad_0086 | Trad_2277 | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.918 |
Trad_0904 | Trad_0086 | Trad_0904 | Trad_0086 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.930 |
Trad_0904 | Trad_1243 | Trad_0904 | Trad_1243 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | 0.923 |
Trad_0904 | Trad_2278 | Trad_0904 | Trad_2278 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | Cysteine synthase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR015424:IPR015421:IPR015422:IPR000277; KEGG: cpc:Cpar_0621 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: Q8KES8 O-acetylhomoserine (Thiol)-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.940 |
Trad_0904 | Trad_2279 | Trad_0904 | Trad_2279 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterProIPR015424:IPR015421:IPR015422:IPR000277:IPR 006235; KEGG: dge:Dgeo_0518 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Q1J114 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | 0.426 |
Trad_0904 | Trad_2519 | Trad_0904 | Trad_2519 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.594 |
Trad_0904 | Trad_2797 | Trad_0904 | Trad_2797 | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR005856:IPR005859:IPR001926; KEGG: dge:Dgeo_1657 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Q1IXT2 Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.965 |
Trad_1243 | Trad_0086 | Trad_1243 | Trad_0086 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.907 |
Trad_1243 | Trad_0904 | Trad_1243 | Trad_0904 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase. | 0.923 |
Trad_1243 | Trad_2278 | Trad_1243 | Trad_2278 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | Cysteine synthase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR015424:IPR015421:IPR015422:IPR000277; KEGG: cpc:Cpar_0621 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: Q8KES8 O-acetylhomoserine (Thiol)-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.900 |
Trad_1243 | Trad_2797 | Trad_1243 | Trad_2797 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase. | COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR005856:IPR005859:IPR001926; KEGG: dge:Dgeo_1657 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Q1IXT2 Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.910 |
Trad_1866 | Trad_0086 | Trad_1866 | Trad_0086 | Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR015424:IPR015421:IPR001176:IPR004839; KEGG: kol:Kole_0146 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: C1XVE0 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II. | Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme. | 0.942 |