STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Trad_2278Cysteine synthase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR015424:IPR015421:IPR015422:IPR000277; KEGG: cpc:Cpar_0621 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: Q8KES8 O-acetylhomoserine (Thiol)-lyase; PFAM: Cys/Met metabolism PLP-dependent enzyme. (463 aa)    
Predicted Functional Partners:
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.969
Trad_2279
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterProIPR015424:IPR015421:IPR015422:IPR000277:IPR 006235; KEGG: dge:Dgeo_0518 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Q1J114 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
 
  
 
0.956
Trad_0904
Nitrite and sulphite reductase 4Fe-4S region; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066:IPR005117:IPR006067; KEGG: chl:Chy400_0742 sulfite reductase (NADPH); PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: C1XVF5 Sulfite reductase (NADPH) beta subunit; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; TIGRFAM: ferredoxin-sulfite reductase.
  
 
 0.940
Trad_0086
Cys/Met metabolism pyridoxal-phosphate-dependent protein; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015421:IPR015422; KEGG: rca:Rcas_3473 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: A7NPM7 Cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme.
 
 
0.935
Trad_2797
COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR005856:IPR005859:IPR001926; KEGG: dge:Dgeo_1657 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Q1IXT2 Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 
 0.920
Trad_1868
Transferase hexapeptide repeat containing protein; COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451; KEGG: gsu:GSU1960 hexapeptide transferase family protein; PFAM: transferase hexapeptide repeat containing protein; SPTR: Q74BU4 Hexapeptide transferase family protein; PFAM: Bacterial transferase hexapeptide (three repeats).
    
 0.918
Trad_1866
Aminotransferase class I and II; COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR015424:IPR015421:IPR001176:IPR004839; KEGG: kol:Kole_0146 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: C1XVE0 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; PFAM: Aminotransferase class I and II.
   
 0.917
Trad_2971
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838:IPR015421:IPR004839:IPR015424; KEGG: dra:DR_0623 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Q9RWP3 Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
   
  0.914
Trad_2519
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.905
Trad_1243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027:IPR003042; KEGG: cag:Cagg_0045 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: B8GC24 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
    
  0.900
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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