STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_2437Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR006153; KEGG: ttj:TTHA1472 Na(+)/H(+) antiporter; PFAM: sodium/hydrogen exchanger; SPTR: B7RZW5 Transporter, CPA2 family; PFAM: Sodium/hydrogen exchanger family. (387 aa)    
Predicted Functional Partners:
Trad_2056
Sodium/hydrogen exchanger; COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR016040:IPR003148:IPR006153; KEGG: cyt:cce_3637 Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; SPTR: B1X0U6 Probable Na+/H+ antiporter; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
   
 0.676
Trad_2672
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterProIPR002178:IPR006153:IPR006016:IPR014729:IPR 016152; KEGG: bha:BH2844 Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; UspA domain protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Q9K908 Na+/H+ antiporter; PFAM: Universal stress protein family; Sodium/hydrogen exchanger family; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
     0.536
Trad_2436
Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: sme:SM_b20975 putative amino acid uptake ABC transporter permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: B6QX10 Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, pe [...]
  
  
 0.500
Trad_1581
Sodium/hydrogen exchanger; COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006015:IPR006153:IPR006016:IPR014729; KEGG: ana:alr2264 Na+/H+-exchanging protein; PFAM: sodium/hydrogen exchanger; UspA domain protein; SPTR: A0ZCU5 Sodium/hydrogen exchanger; PFAM: Universal stress protein family; Sodium/hydrogen exchanger family.
   
 
 0.498
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.413
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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