STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Trad_2663Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR012318:IPR001808:IPR014710:IPR 011991:IPR018490; KEGG: tth:TT_P0055 regulatory protein; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: regulatory protein Crp; cyclic nucleotide-binding; SPTR: B7AAU6 Transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain. (213 aa)    
Predicted Functional Partners:
Trad_2673
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR012318:IPR001808:IPR014710:IPR 011991:IPR018490; KEGG: dge:Dgeo_0106 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Q1J275 Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
     0.772
Trad_1652
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR014710:IPR018490:IPR012318; KEGG: sus:Acid_2932 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: C1XRF8 cAMP-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
     0.766
Trad_2664
Regulatory protein MerR; COGs: COG5012 cobalamin binding protein; InterPro IPR000551:IPR006158:IPR009061; KEGG: chl:Chy400_2902 regulatory protein MerR; PFAM: regulatory protein MerR; cobalamin B12-binding domain protein; SMART: regulatory protein MerR; SPTR: C1XVR4 Transcriptional regulator, MerR family; manually curated; PFAM: MerR family regulatory protein; B12 binding domain.
     
 0.630
Trad_2846
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: fal:FRAAL0057 putative adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: C9NAV2 Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
 
 0.565
Trad_2898
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000160:IPR003018:IPR001610:IPR 001633:IPR000700:IPR013656:IPR013767; KEGG: ddr:Deide_1p00099 putative diguanylate-cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; GAF domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: C [...]
  
 
 0.501
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.409
Trad_0434
Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
  
     0.403
Your Current Organism:
Truepera radiovictrix
NCBI taxonomy Id: 649638
Other names: T. radiovictrix DSM 17093, Truepera radiovictrix DSM 17093, Truepera radiovictrix RQ-24, Truepera radiovictrix str. DSM 17093, Truepera radiovictrix strain DSM 17093
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