Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADU30170.1KEGG: afl:Aflv_1130 predicted hydrolase (metallo-beta-lactamase superfamily). (291 aa)    
Predicted Functional Partners:
ADU30168.1
PFAM: Tetratricopeptide TPR_1 repeat-containing protein; KEGG: bpf:BpOF4_15615 hypothetical protein.
 
     0.825
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
       0.764
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
       0.685
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
       0.615
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
       0.615
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.615
ADU30173.1
KEGG: hypothetical protein.
       0.590
ADU30479.1
KEGG: ate:Athe_1955 spore germination protein; TIGRFAM: spore germination protein; PFAM: Spore germination protein.
  
     0.555
ADU29017.1
Helix-turn-helix domain protein; KEGG: oih:OB2597 transcriptional activator; PFAM: helix-turn-helix domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: helix-turn-helix domain protein; Tetratricopeptide repeat.
 
     0.492
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.485
Your Current Organism:
Bacillus cellulosilyticus
NCBI taxonomy Id: 649639
Other names: B. cellulosilyticus DSM 2522, Bacillus cellulosilyticus DSM 2522, Bacillus cellulosilyticus str. DSM 2522, Bacillus cellulosilyticus strain DSM 2522, Bacillus sp. (STRAIN N-4), Bacillus sp. ATCC 21833, Bacillus sp. N-4
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