STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU31447.1KEGG: primosomal DnaI domain protein; PFAM: Primosomal DnaI domain protein; IstB domain protein ATP-binding protein; SMART: AAA ATPase. (311 aa)    
Predicted Functional Partners:
ADU31448.1
TIGRFAM: primosome, DnaD subunit; KEGG: bha:BH3145 chromosome replication initiation/membrane attachment protein.
 
  
 0.959
ADU32536.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.842
ADU30175.1
TIGRFAM: primosome, DnaD subunit; KEGG: gwc:GWCH70_2110 primosome, DnaD subunit.
 
  
 0.798
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.756
ADU31450.1
KEGG: hypothetical protein.
       0.668
ADU29791.1
PFAM: protein of unknown function DUF1292; KEGG: protein of unknown function DUF1292; Belongs to the UPF0473 family.
  
     0.651
ADU31661.1
PFAM: protein of unknown function DUF1027; KEGG: bpf:BpOF4_04940 hypothetical protein.
  
     0.650
rpoE
DNA-directed RNA polymerase delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
  
     0.649
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
   
 0.627
ADU30866.1
PFAM: protein of unknown function DUF177; KEGG: protein of unknown function DUF177.
 
     0.591
Your Current Organism:
Bacillus cellulosilyticus
NCBI taxonomy Id: 649639
Other names: B. cellulosilyticus DSM 2522, Bacillus cellulosilyticus DSM 2522, Bacillus cellulosilyticus str. DSM 2522, Bacillus cellulosilyticus strain DSM 2522, Bacillus sp. (STRAIN N-4), Bacillus sp. ATCC 21833, Bacillus sp. N-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.