SEI37496.1 protein (Pseudospirillum japonicum)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Coexpression

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Score

SEI37496.1

Methyl-accepting chemotaxis protein. (480 aa)

Predicted Functional Partners:

SEI37226.1

0.976

SEI63957.1

0.968

SEI76300.1

0.968

SEI46046.1

0.967

SEI60611.1

0.965

SEI37353.1

0.946

SEI41734.1

0.944

SEI37460.1

0.943

SEI44950.1

0.943

SEI82366.1

0.943

Your Current Organism:

Pseudospirillum japonicum

NCBI taxonomy Id: 64971
Other names: ATCC 19191, CIP 103373, DSM 7165, IFO 15446, LMG 10146, LMG:10146, NBRC 15446, Oceanospirillum japonicum, P. japonicum, Spirillum japonicum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SEI37226.1	SEI37353.1	SAMN05421831_1017	SAMN05421831_10126	Two-component system, chemotaxis family, CheB/CheR fusion protein.	PAS domain S-box-containing protein.	0.999
SEI37226.1	SEI37460.1	SAMN05421831_1017	SAMN05421831_10145	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999
SEI37226.1	SEI37496.1	SAMN05421831_1017	SAMN05421831_10151	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Methyl-accepting chemotaxis protein.	0.976
SEI37226.1	SEI41734.1	SAMN05421831_1017	SAMN05421831_101410	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Hypothetical protein.	0.999
SEI37226.1	SEI44950.1	SAMN05421831_1017	SAMN05421831_10240	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999
SEI37226.1	SEI46046.1	SAMN05421831_1017	SAMN05421831_102126	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.999
SEI37226.1	SEI60611.1	SAMN05421831_1017	SAMN05421831_10592	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.999
SEI37226.1	SEI63957.1	SAMN05421831_1017	SAMN05421831_10646	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.999
SEI37226.1	SEI76300.1	SAMN05421831_1017	SAMN05421831_109117	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.999
SEI37226.1	SEI82366.1	SAMN05421831_1017	SAMN05421831_11156	Two-component system, chemotaxis family, CheB/CheR fusion protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999
SEI37353.1	SEI37226.1	SAMN05421831_10126	SAMN05421831_1017	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, CheB/CheR fusion protein.	0.999
SEI37353.1	SEI37460.1	SAMN05421831_10126	SAMN05421831_10145	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999
SEI37353.1	SEI37496.1	SAMN05421831_10126	SAMN05421831_10151	PAS domain S-box-containing protein.	Methyl-accepting chemotaxis protein.	0.946
SEI37353.1	SEI41734.1	SAMN05421831_10126	SAMN05421831_101410	PAS domain S-box-containing protein.	Hypothetical protein.	0.999
SEI37353.1	SEI44950.1	SAMN05421831_10126	SAMN05421831_10240	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999
SEI37353.1	SEI46046.1	SAMN05421831_10126	SAMN05421831_102126	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.989
SEI37353.1	SEI60611.1	SAMN05421831_10126	SAMN05421831_10592	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.989
SEI37353.1	SEI63957.1	SAMN05421831_10126	SAMN05421831_10646	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.989
SEI37353.1	SEI76300.1	SAMN05421831_10126	SAMN05421831_109117	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, sensor kinase CheA.	0.989
SEI37353.1	SEI82366.1	SAMN05421831_10126	SAMN05421831_11156	PAS domain S-box-containing protein.	Two-component system, chemotaxis family, response regulator CheV.	0.999

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Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

1.23e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046417

Chorismate metabolic process

7 of 10

2.51

6.15

3.95e-13

GO:0009073

Aromatic amino acid family biosynthetic process

6 of 15

2.27

4.51

3.75e-10

GO:0009423

Chorismate biosynthetic process

5 of 8

2.46

4.25

4.57e-09

GO:0016053

Organic acid biosynthetic process

8 of 158

1.37

2.06

2.70e-08

GO:0008652

Cellular amino acid biosynthetic process

6 of 99

1.45

1.91

2.07e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016838

Carbon-oxygen lyase activity, acting on phosphates

3 of 5

2.45

1.93

0.00025

GO:0003856

3-dehydroquinate synthase activity

2 of 2

2.67

1.16

0.0077

GO:0004106

Chorismate mutase activity

2 of 3

2.49

1.13

0.0085

GO:0003824

Catalytic activity

11 of 2353

0.34

0.26

0.0241

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 1151

0.56

0.41

0.0065

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:831

Aromatic amino acid family metabolic process, and Anthranilate synthase component I-like

7 of 17

2.28

5.23

6.87e-12

CL:833

Prephenate dehydratase, and Enolpyruvate transferase domain

4 of 5

2.57

3.38

4.03e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

8 of 25

2.17

5.85

2.40e-14

map01230

Biosynthesis of amino acids

8 of 140

1.42

2.31

3.82e-09

map01110

Biosynthesis of secondary metabolites

8 of 486

0.88

0.85

3.72e-05

map01100

Metabolic pathways

11 of 1481

0.54

0.47

3.85e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

6 of 388

0.86

0.59

0.0085

GOCC:0005737

Cytoplasm

9 of 957

0.64

0.49

0.0029

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0057

Aromatic amino acid biosynthesis

4 of 12

2.19

2.69

4.26e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01761

3-dehydroquinate synthase

2 of 2

2.67

0.99

0.0159

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036979

Chorismate mutase domain superfamily

2 of 2

2.67

0.78

0.0384

IPR036263

Chorismate mutase type II superfamily

2 of 2

2.67

0.78

0.0384

IPR030960

3-dehydroquinate synthase domain

2 of 2

2.67

0.78

0.0384

IPR002701

Chorismate mutase II, prokaryotic-type

2 of 2

2.67

0.78

0.0384

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00830

Chorismate mutase type II

2 of 2

2.67

1.37

0.0032

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