STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proSproline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (569 aa)    
Predicted Functional Partners:
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.978
ERI08505.1
Hypothetical protein; KEGG: bmq:BMQ_2736 9.7e-76 ileS; isoleucyl-tRNA synthetase K01870; Psort location: Cytoplasmic, score: 9.97.
   
 0.976
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
   
 0.976
ERI09220.1
KEGG: ppo:PPM_1896 3.5e-126 fliY3; flagellar motor switch phosphatase fliY CheY-P phosphatase fliY; Flagellar motor switch protein fliY K02417; Psort location: CytoplasmicMembrane, score: 8.78.
   
   0.972
argS
arginine--tRNA ligase; KEGG: bpf:BpOF4_07110 1.4e-207 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.97.
  
 0.967
asnS
asparagine--tRNA ligase; KEGG: bbe:BBR47_25160 1.1e-186 asnS; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00.
  
 
 0.966
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.964
glnS
glutamine--tRNA ligase; KEGG: bbe:BBR47_55490 2.9e-257 glnS; glutaminyl-tRNA synthetase K01886; Psort location: Cytoplasmic, score: 9.97.
  
 0.958
lysS
lysine--tRNA ligase; KEGG: bpf:BpOF4_08385 4.1e-203 lysS; lysyl-tRNA synthetase K04567; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.948
leuS
leucine--tRNA ligase; KEGG: bts:Btus_1210 3.7e-296 leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.939
Your Current Organism:
Aneurinibacillus aneurinilyticus
NCBI taxonomy Id: 649747
Other names: A. aneurinilyticus ATCC 12856, Aneurinibacillus aneurinilyticus ATCC 12856, Aneurinibacillus aneurinilyticus DSM 5562, Aneurinibacillus aneurinilyticus str. ATCC 12856, Aneurinibacillus aneurinilyticus strain ATCC 12856
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