STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa)    
Predicted Functional Partners:
ERI07270.1
5'-3' exonuclease, SAM domain protein; KEGG: bmq:BMQ_2009 1.4e-51 DNA polymerase I; Psort location: Cytoplasmic, score: 7.50.
 
 0.992
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
 
 0.990
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 0.982
ERI08694.1
KEGG: bss:BSUW23_03355 5.3e-265 pcrA; ATP-dependent DNA helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.941
ERI10079.1
KEGG: bbe:BBR47_24270 2.4e-104 recQ; ATP-dependent DNA helicase K03654; Psort location: Cytoplasmic, score: 9.89.
  
 0.939
ERI04306.1
HRDC domain protein; KEGG: bpf:BpOF4_18875 1.9e-12 recS; ATP-dependent DNA helicase RecS; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 7.50.
  
 0.933
ERI10873.1
LexA DNA binding domain protein; KEGG: bpf:BpOF4_19445 8.1e-24 lexA; LexA repressor; K01356 repressor LexA.
  
 
 0.932
ERI10823.1
Repressor LexA; KEGG: bbe:BBR47_33080 3.0e-26 lexA; LexA repressor K01356; Psort location: CytoplasmicMembrane, score: 8.16.
  
 
 0.932
ERI09724.1
LexA DNA binding domain protein; KEGG: gth:Geoth_2571 1.5e-15 SOS-response transcriptional repressor, LexA; K01356 repressor LexA.
  
 
 0.932
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.932
Your Current Organism:
Aneurinibacillus aneurinilyticus
NCBI taxonomy Id: 649747
Other names: A. aneurinilyticus ATCC 12856, Aneurinibacillus aneurinilyticus ATCC 12856, Aneurinibacillus aneurinilyticus DSM 5562, Aneurinibacillus aneurinilyticus str. ATCC 12856, Aneurinibacillus aneurinilyticus strain ATCC 12856
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