node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hemC | ribA | ERS852387_01092 | ERS852387_00709 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.620 |
hemC | ribD | ERS852387_01092 | ERS852387_00707 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | Riboflavin biosynthesis protein RibD. | 0.792 |
hemC | ribE | ERS852387_01092 | ERS852387_00708 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | Riboflavin synthase alpha chain. | 0.623 |
hemC | ribF | ERS852387_01092 | ERS852387_01266 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | Riboflavin biosynthesis protein ribF; Belongs to the ribF family. | 0.767 |
hemC | ribH | ERS852387_01092 | ERS852387_00710 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | 6%2C7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.709 |
hemC | rpmE | ERS852387_01092 | ERS852387_00518 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | 50S ribosomal protein L31; Binds the 23S rRNA. | 0.400 |
hemC | secDF | ERS852387_01092 | ERS852387_02223 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.526 |
hemC | sulD | ERS852387_01092 | ERS852387_00919 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.844 |
lsrK | ribA | ERS852387_00711 | ERS852387_00709 | Autoinducer 2 kinase LsrK. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.482 |
lsrK | ribD | ERS852387_00711 | ERS852387_00707 | Autoinducer 2 kinase LsrK. | Riboflavin biosynthesis protein RibD. | 0.434 |
lsrK | ribE | ERS852387_00711 | ERS852387_00708 | Autoinducer 2 kinase LsrK. | Riboflavin synthase alpha chain. | 0.434 |
lsrK | ribH | ERS852387_00711 | ERS852387_00710 | Autoinducer 2 kinase LsrK. | 6%2C7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.668 |
ribA | hemC | ERS852387_00709 | ERS852387_01092 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | 0.620 |
ribA | lsrK | ERS852387_00709 | ERS852387_00711 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Autoinducer 2 kinase LsrK. | 0.482 |
ribA | ribD | ERS852387_00709 | ERS852387_00707 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibD. | 0.999 |
ribA | ribE | ERS852387_00709 | ERS852387_00708 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Riboflavin synthase alpha chain. | 0.999 |
ribA | ribH | ERS852387_00709 | ERS852387_00710 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 6%2C7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribA | secDF | ERS852387_00709 | ERS852387_02223 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.454 |
ribA | sulD | ERS852387_00709 | ERS852387_00919 | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | Bifunctional folate synthesis protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.719 |
ribD | hemC | ERS852387_00707 | ERS852387_01092 | Riboflavin biosynthesis protein RibD. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. | 0.792 |