node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFB31098.1 | folB | HMPREF0971_02657 | HMPREF0971_00503 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.965 |
EFB31098.1 | folC | HMPREF0971_02657 | HMPREF0971_02686 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | 0.434 |
EFB31098.1 | folE | HMPREF0971_02657 | HMPREF0971_00630 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | GTP cyclohydrolase I; KEGG: bfs:BF3727 1.7e-74 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.666 |
EFB31098.1 | folK | HMPREF0971_02657 | HMPREF0971_00649 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3216 5.2e-32 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine K00950. | 0.900 |
EFB31098.1 | folP | HMPREF0971_02657 | HMPREF0971_01983 | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3646 3.4e-76 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.965 |
dacA | folP | HMPREF0971_01982 | HMPREF0971_01983 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: bth:BT3646 3.4e-76 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.629 |
dacA | murF | HMPREF0971_01982 | HMPREF0971_01984 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.641 |
dacA | pta | HMPREF0971_01982 | HMPREF0971_01981 | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | KEGG: bth:BT3692 3.3e-124 phosphate acetyltransferase K00625; Psort location: Cytoplasmic, score: 8.96. | 0.672 |
dnaK | folE | HMPREF0971_03193 | HMPREF0971_00630 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GTP cyclohydrolase I; KEGG: bfs:BF3727 1.7e-74 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.564 |
dnaK | folP | HMPREF0971_03193 | HMPREF0971_01983 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | KEGG: bth:BT3646 3.4e-76 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.587 |
dnaK | guaB | HMPREF0971_03193 | HMPREF0971_00923 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.489 |
folB | EFB31098.1 | HMPREF0971_00503 | HMPREF0971_02657 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | 0.965 |
folB | folC | HMPREF0971_00503 | HMPREF0971_02686 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | 0.552 |
folB | folE | HMPREF0971_00503 | HMPREF0971_00630 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I; KEGG: bfs:BF3727 1.7e-74 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.937 |
folB | folK | HMPREF0971_00503 | HMPREF0971_00649 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: bth:BT3216 5.2e-32 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine K00950. | 0.985 |
folB | folP | HMPREF0971_00503 | HMPREF0971_01983 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: bth:BT3646 3.4e-76 dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 8.96. | 0.994 |
folC | EFB31098.1 | HMPREF0971_02686 | HMPREF0971_02657 | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | Putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; KEGG: hch:HCH_06267 1.6e-07 folK2; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950; Psort location: Cytoplasmic, score: 8.96. | 0.434 |
folC | folB | HMPREF0971_02686 | HMPREF0971_00503 | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.552 |
folC | folE | HMPREF0971_02686 | HMPREF0971_00630 | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I; KEGG: bfs:BF3727 1.7e-74 folE, mtrA; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96. | 0.552 |
folC | folK | HMPREF0971_02686 | HMPREF0971_00649 | Bifunctional protein FolC; KEGG: bfs:BF2850 8.2e-121 putative folylpolyglutamate synthase K01930; Belongs to the folylpolyglutamate synthase family. | KEGG: bth:BT3216 5.2e-32 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine K00950. | 0.462 |