node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFB30894.1 | UvrA_1 | HMPREF0971_02782 | HMPREF0971_02783 | Hypothetical protein. | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.550 |
EFB30894.1 | uvrA-2 | HMPREF0971_02782 | HMPREF0971_02784 | Hypothetical protein. | KEGG: reh:H16_A0400 3.4e-89 uvrA1; excinuclease ABC, ATPase subunit (A) K01529. | 0.483 |
EFB30897.1 | EFB30898.1 | HMPREF0971_02785 | HMPREF0971_02786 | Hypothetical protein; KEGG: chu:CHU_3440 1.9e-05 CHU large protein; glycoside hydrolase family 8 protein, beta-glycosidase related K01238. | Hypothetical protein. | 0.698 |
EFB30897.1 | UvrA_1 | HMPREF0971_02785 | HMPREF0971_02783 | Hypothetical protein; KEGG: chu:CHU_3440 1.9e-05 CHU large protein; glycoside hydrolase family 8 protein, beta-glycosidase related K01238. | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.571 |
EFB30897.1 | uvrA-2 | HMPREF0971_02785 | HMPREF0971_02784 | Hypothetical protein; KEGG: chu:CHU_3440 1.9e-05 CHU large protein; glycoside hydrolase family 8 protein, beta-glycosidase related K01238. | KEGG: reh:H16_A0400 3.4e-89 uvrA1; excinuclease ABC, ATPase subunit (A) K01529. | 0.635 |
EFB30898.1 | EFB30897.1 | HMPREF0971_02786 | HMPREF0971_02785 | Hypothetical protein. | Hypothetical protein; KEGG: chu:CHU_3440 1.9e-05 CHU large protein; glycoside hydrolase family 8 protein, beta-glycosidase related K01238. | 0.698 |
EFB30898.1 | UvrA_1 | HMPREF0971_02786 | HMPREF0971_02783 | Hypothetical protein. | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.555 |
EFB30898.1 | uvrA-2 | HMPREF0971_02786 | HMPREF0971_02784 | Hypothetical protein. | KEGG: reh:H16_A0400 3.4e-89 uvrA1; excinuclease ABC, ATPase subunit (A) K01529. | 0.588 |
UvrA_1 | EFB30894.1 | HMPREF0971_02783 | HMPREF0971_02782 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Hypothetical protein. | 0.550 |
UvrA_1 | EFB30897.1 | HMPREF0971_02783 | HMPREF0971_02785 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Hypothetical protein; KEGG: chu:CHU_3440 1.9e-05 CHU large protein; glycoside hydrolase family 8 protein, beta-glycosidase related K01238. | 0.571 |
UvrA_1 | EFB30898.1 | HMPREF0971_02783 | HMPREF0971_02786 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Hypothetical protein. | 0.555 |
UvrA_1 | mfd | HMPREF0971_02783 | HMPREF0971_02286 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.718 |
UvrA_1 | mutL | HMPREF0971_02783 | HMPREF0971_00918 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.440 |
UvrA_1 | polA | HMPREF0971_02783 | HMPREF0971_01746 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.439 |
UvrA_1 | uvrA | HMPREF0971_02783 | HMPREF0971_01347 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.903 |
UvrA_1 | uvrA-2 | HMPREF0971_02783 | HMPREF0971_02784 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | KEGG: reh:H16_A0400 3.4e-89 uvrA1; excinuclease ABC, ATPase subunit (A) K01529. | 0.976 |
UvrA_1 | uvrB | HMPREF0971_02783 | HMPREF0971_00121 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.979 |
UvrA_1 | uvrC | HMPREF0971_02783 | HMPREF0971_01755 | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.864 |
mfd | UvrA_1 | HMPREF0971_02286 | HMPREF0971_02783 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Putative excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.718 |
mfd | mutL | HMPREF0971_02286 | HMPREF0971_00918 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.512 |