STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEX18998.1UvrD/REP helicase; KEGG: chu:CHU_1554 4.9e-37 uvrD; ATP-dependent DNA helicase II K03657; Psort location: Cytoplasmic, score: 8.96. (896 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.940
dnaN
KEGG: bth:BT1364 1.6e-92 DNA polymerase III, beta chain K02338.
  
 0.915
EEX18104.1
UvrD/REP helicase; KEGG: bfs:BF2555 8.9e-227 putative helicase K03657.
 
 
0.900
ligA
NAD-dependent DNA ligase OB-fold domain protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
 
 
 0.890
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.878
recQ
KEGG: bth:BT3844 7.7e-276 recQ; ATP-dependent DNA helicase recQ K03654; Psort location: Cytoplasmic, score: 8.96.
  
 0.872
EEX19098.1
KEGG: bfr:BF3933 1.9e-194 recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 8.96.
  
 0.872
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.866
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.865
EEX19610.1
Hypothetical protein.
   
 
 0.835
Your Current Organism:
Prevotella veroralis
NCBI taxonomy Id: 649761
Other names: P. veroralis F0319, Prevotella veroralis F0319, Prevotella veroralis str. F0319, Prevotella veroralis strain F0319
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