node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEX18258.1 | EEX18465.1 | HMPREF0973_01853 | HMPREF0973_01658 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 0.426 |
EEX18258.1 | guaA | HMPREF0973_01853 | HMPREF0973_01678 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.667 |
EEX18258.1 | guaB | HMPREF0973_01853 | HMPREF0973_00688 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.750 |
EEX18258.1 | purC | HMPREF0973_01853 | HMPREF0973_01856 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT4217 3.1e-121 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family. | 0.985 |
EEX18258.1 | purD | HMPREF0973_01853 | HMPREF0973_00441 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | KEGG: bth:BT3253 1.0e-154 phosphoribosylamine--glycine ligase K01945; Belongs to the GARS family. | 0.954 |
EEX18258.1 | purE | HMPREF0973_01853 | HMPREF0973_01405 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.936 |
EEX18258.1 | purL | HMPREF0973_01853 | HMPREF0973_01124 | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
EEX18463.1 | EEX18464.1 | HMPREF0973_01656 | HMPREF0973_01657 | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Hydrolase, NUDIX family; KEGG: bth:BT1544 5.7e-74 NADH pyrophosphatase, MutT family hydrolase K03659. | 0.817 |
EEX18463.1 | EEX18465.1 | HMPREF0973_01656 | HMPREF0973_01658 | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 0.681 |
EEX18463.1 | guaA | HMPREF0973_01656 | HMPREF0973_01678 | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.493 |
EEX18463.1 | guaB | HMPREF0973_01656 | HMPREF0973_00688 | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.729 |
EEX18464.1 | EEX18463.1 | HMPREF0973_01657 | HMPREF0973_01656 | Hydrolase, NUDIX family; KEGG: bth:BT1544 5.7e-74 NADH pyrophosphatase, MutT family hydrolase K03659. | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | 0.817 |
EEX18464.1 | EEX18465.1 | HMPREF0973_01657 | HMPREF0973_01658 | Hydrolase, NUDIX family; KEGG: bth:BT1544 5.7e-74 NADH pyrophosphatase, MutT family hydrolase K03659. | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 0.772 |
EEX18465.1 | EEX18258.1 | HMPREF0973_01658 | HMPREF0973_01853 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; KEGG: bfr:BF0911 3.1e-176 putative phosphoribosylformylglycinamidine cyclo-ligase K01933; Psort location: Cytoplasmic, score: 8.96. | 0.426 |
EEX18465.1 | EEX18463.1 | HMPREF0973_01658 | HMPREF0973_01656 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 5'-nucleotidase, C-terminal domain protein; KEGG: bth:BT1236 1.8e-157 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor K01119; Psort location: Periplasmic, score: 9.44; Belongs to the 5'-nucleotidase family. | 0.681 |
EEX18465.1 | EEX18464.1 | HMPREF0973_01658 | HMPREF0973_01657 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | Hydrolase, NUDIX family; KEGG: bth:BT1544 5.7e-74 NADH pyrophosphatase, MutT family hydrolase K03659. | 0.772 |
EEX18465.1 | guaA | HMPREF0973_01658 | HMPREF0973_01678 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.570 |
EEX18465.1 | guaB | HMPREF0973_01658 | HMPREF0973_00688 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.527 |
EEX18465.1 | pdxB | HMPREF0973_01658 | HMPREF0973_00397 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 4-phosphoerythronate dehydrogenase; KEGG: bfs:BF1389 2.8e-111 ldhA, hslI, htpH; putative D-lactate dehydrogenase K03778; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.428 |
EEX18465.1 | purC | HMPREF0973_01658 | HMPREF0973_01856 | Putative permease; KEGG: bcz:BCZK0244 4.1e-87 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: bth:BT4217 3.1e-121 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family. | 0.447 |