STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (420 aa)    
Predicted Functional Partners:
EEZ60557.1
Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 2.3e-93 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; Psort location: Cytoplasmic, score: 8.87.
  
 0.968
EEZ61358.1
Hypothetical protein; KEGG: pca:Pcar_2722 2.6e-19 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation K00548; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.908
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
  
    0.778
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
    
 0.737
EEZ61870.1
Aminotransferase, class I/II; KEGG: blo:BL0712 1.6e-197 aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 8.87.
  
 0.718
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.699
EEZ61622.1
Aminotransferase, class I/II; KEGG: cac:CAC2832 8.6e-110 PLP-dependent aminotransferase K00811; Psort location: Cytoplasmic, score: 8.87.
  
 0.685
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 
 0.657
ksgA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
    
 0.652
arcT
Dipeptidase; KEGG: sai:Saci_1837 1.4e-47 aspartate aminotransferase K00812; Psort location: Cytoplasmic, score: 8.87.
  
 0.645
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.