STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ62026.16-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (163 aa)    
Predicted Functional Partners:
EEZ60837.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
      0.845
rpe
KEGG: ade:Adeh_3971 5.4e-46 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 8.87.
  
    0.647
EEZ62029.1
Putative dinuclear metal center protein, YbgI family.
       0.619
EEZ62028.1
Aminotransferase, class V; KEGG: fal:FRAAL5862 1.6e-76 iscS; cysteine desulfurase K04487; Psort location: Cytoplasmic, score: 8.87.
       0.601
EEZ62030.1
Putative zinc ribbon domain protein; KEGG: eci:UTI89_C0735 0.00028 tolA; membrane spanning protein TolA K03646; Psort location: Cytoplasmic, score: 8.87.
       0.578
EEZ62025.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.572
recJ
KEGG: tte:TTE1191 5.3e-94 recJ; Single-stranded DNA-specific exonuclease K07462; Psort location: Cytoplasmic, score: 8.87.
     
 0.482
EEZ62031.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.462
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.448
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.431
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.