STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (219 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease III; KEGG: lmf:LMOf2365_1807 3.0e-84 exoA; exodeoxyribonuclease K01142; Psort location: Cytoplasmic, score: 9.98.
 
 0.998
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
   
 0.702
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.693
EEZ61277.1
Base excision DNA repair protein, HhH-GPD family; KEGG: gsu:GSU1613 1.6e-53 A/G-specific adenine glycosylase, putative K03575; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.670
EEZ62096.1
Cyclic nucleotide-binding domain protein; KEGG: reh:H16_B1422 1.4e-07 thioredoxin reductase K00384; Psort location: Cytoplasmic, score: 8.87.
       0.517
EEZ62144.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecc:c2001 0.00025 rstB; sensor protein rstB K07639.
    
 
 0.501
recJ
KEGG: tte:TTE1191 5.3e-94 recJ; Single-stranded DNA-specific exonuclease K07462; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.467
EEZ61121.1
Putative DnaQ family exonuclease/DinG family helicase; KEGG: sth:STH1713 5.3e-94 ATP-dependent DNA helicase K03722; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.411
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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