STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lexARepressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (232 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.960
EEZ62076.1
KEGG: gsu:GSU1616 2.8e-41 ImpB/MucB/SamB family protein K02346; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.806
EEZ60386.1
ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 4.6e-56 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.755
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.656
EEZ62277.1
KEGG: bcl:ABC1086 1.1e-162 pcrA; ATP-dependent DNA helicase, UvrD/REP family K03657; Psort location: Cytoplasmic, score: 8.87.
     
 0.569
EEZ62138.1
Hypothetical protein.
       0.562
EEZ61121.1
Putative DnaQ family exonuclease/DinG family helicase; KEGG: sth:STH1713 5.3e-94 ATP-dependent DNA helicase K03722; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.531
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.513
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
   
 0.484
argR
Arginine repressor, C-terminal domain protein; Regulates arginine biosynthesis genes.
  
   
 0.479
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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