STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (259 aa)    
Predicted Functional Partners:
EEZ61781.1
Phosphopantetheine attachment domain protein; KEGG: rha:RHA1_ro00144 1.1e-05 non-ribosomal peptide synthetase K01779:K03367; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.877
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.854
queH
Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
 
      0.777
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.762
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.756
recJ
KEGG: tte:TTE1191 5.3e-94 recJ; Single-stranded DNA-specific exonuclease K07462; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.755
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
   
 0.747
EEZ61121.1
Putative DnaQ family exonuclease/DinG family helicase; KEGG: sth:STH1713 5.3e-94 ATP-dependent DNA helicase K03722; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.665
EEZ61785.1
AMP-binding enzyme; KEGG: rpb:RPB_0580 6.6e-15 AMP-dependent synthetase and ligase K01897; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.646
lepB
Signal peptidase I; KEGG: rxy:Rxyl_0250 3.8e-29 peptidase S26A, signal peptidase I K03100; Psort location: CytoplasmicMembrane, score: 9.82.
  
    0.608
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.