STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (421 aa)    
Predicted Functional Partners:
EEZ62028.1
Aminotransferase, class V; KEGG: fal:FRAAL5862 1.6e-76 iscS; cysteine desulfurase K04487; Psort location: Cytoplasmic, score: 8.87.
  
 0.846
EEZ60532.1
KEGG: tte:TTE2465 4.0e-89 nifS2; cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; Psort location: Cytoplasmic, score: 8.87.
 
 0.846
EEZ61665.1
Aminotransferase, class V; KEGG: mta:Moth_0199 2.2e-56 aminotransferase, class V K04487; Psort location: Cytoplasmic, score: 8.87.
 
 0.810
EEZ62024.1
NusB family protein; KEGG: bha:BH2507 1.5e-41 Sun protein K03500; Psort location: Cytoplasmic, score: 8.87; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
    0.807
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.650
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
       0.648
EEZ62192.1
Hypothetical protein; KEGG: twh:TWT363 3.8e-05 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score: 8.87.
       0.624
holA
KEGG: gme:Gmet_2298 1.3e-26 DNA polymerase III, delta subunit K02340.
 
    0.607
EEZ62187.1
DNA internalization competence protein ComEC/Rec2-like protein; Psort location: CytoplasmicMembrane, score: 9.97.
       0.575
EEZ62238.1
NOL1/NOP2/sun family protein; KEGG: eci:UTI89_C2036 2.0e-32 yebU; hypothetical protein YebU K00555; Psort location: Cytoplasmic, score: 8.87.
   
    0.563
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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