STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrRPhosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (195 aa)    
Predicted Functional Partners:
pyrB
KEGG: pca:Pcar_1615 2.2e-81 aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.997
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.993
pyrC
Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.986
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.969
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.950
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.913
EEZ62195.1
Oxidoreductase NAD-binding domain protein; KEGG: cno:NT01CX_0392 1.7e-33 dihydroorotate dehydrogenase electron transfer subunit K00226; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.910
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.866
carB
KEGG: afu:AF1274 0. carB; carbamoyl-phosphate synthase large chain K01955; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarB family.
  
  
 0.778
carA
KEGG: pca:Pcar_1613 9.0e-99 carbamoyl-phosphate synthase small subunit K01956; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family.
  
  
 0.717
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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