| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEZ61656.1 | EEZ62200.1 | HMPREF0762_00997 | HMPREF0762_00292 | Putative sortase, SrtB family. | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.407 |
| EEZ62199.1 | EEZ62200.1 | HMPREF0762_00291 | HMPREF0762_00292 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.973 |
| EEZ62199.1 | EEZ62201.1 | HMPREF0762_00291 | HMPREF0762_00293 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 8.87. | 0.561 |
| EEZ62199.1 | EEZ62202.1 | HMPREF0762_00291 | HMPREF0762_00294 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.431 |
| EEZ62199.1 | EEZ62203.1 | HMPREF0762_00291 | HMPREF0762_00295 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Hydrogenase maturation protease; KEGG: gme:Gmet_3329 1.8e-13 peptidase M52, hydrogenase maturation peptidase K03605; Psort location: Cytoplasmic, score: 8.87. | 0.431 |
| EEZ62199.1 | pyrB | HMPREF0762_00291 | HMPREF0762_00289 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | KEGG: pca:Pcar_1615 2.2e-81 aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.402 |
| EEZ62199.1 | pyrC | HMPREF0762_00291 | HMPREF0762_00288 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.402 |
| EEZ62199.1 | pyrD | HMPREF0762_00291 | HMPREF0762_00286 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.400 |
| EEZ62199.1 | pyrF | HMPREF0762_00291 | HMPREF0762_00285 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.400 |
| EEZ62199.1 | pyrR | HMPREF0762_00291 | HMPREF0762_00290 | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.402 |
| EEZ62200.1 | EEZ61656.1 | HMPREF0762_00292 | HMPREF0762_00997 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Putative sortase, SrtB family. | 0.407 |
| EEZ62200.1 | EEZ62199.1 | HMPREF0762_00292 | HMPREF0762_00291 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; KEGG: eci:UTI89_C4143 6.2e-17 putative autotransport adhesin K01423; Psort location: Cellwall, score: 9.17. | 0.973 |
| EEZ62200.1 | EEZ62201.1 | HMPREF0762_00292 | HMPREF0762_00293 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Transcriptional regulator, TetR family; Psort location: Cytoplasmic, score: 8.87. | 0.520 |
| EEZ62200.1 | EEZ62202.1 | HMPREF0762_00292 | HMPREF0762_00294 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. | 0.431 |
| EEZ62200.1 | EEZ62203.1 | HMPREF0762_00292 | HMPREF0762_00295 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Hydrogenase maturation protease; KEGG: gme:Gmet_3329 1.8e-13 peptidase M52, hydrogenase maturation peptidase K03605; Psort location: Cytoplasmic, score: 8.87. | 0.431 |
| EEZ62200.1 | pyrB | HMPREF0762_00292 | HMPREF0762_00289 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | KEGG: pca:Pcar_1615 2.2e-81 aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.402 |
| EEZ62200.1 | pyrC | HMPREF0762_00292 | HMPREF0762_00288 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.402 |
| EEZ62200.1 | pyrD | HMPREF0762_00292 | HMPREF0762_00286 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. | 0.414 |
| EEZ62200.1 | pyrF | HMPREF0762_00292 | HMPREF0762_00285 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.400 |
| EEZ62200.1 | pyrR | HMPREF0762_00292 | HMPREF0762_00290 | MMPL family protein; Psort location: CytoplasmicMembrane, score: 9.99. | Phosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.402 |