STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrCThreonine synthase; KEGG: blo:BL1036 3.8e-139 thrC; threonine synthase K01733; Psort location: Cytoplasmic, score: 8.87. (493 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.999
EEZ60993.1
KEGG: chy:CHY_1912 2.3e-93 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
 
 0.952
ilvA
KEGG: fnu:FN1411 1.3e-113 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.908
EEZ62255.1
Amino acid kinase family; KEGG: cno:NT01CX_0187 1.1e-107 aspartate kinase, putative K00928; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family.
 
 
 0.897
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.750
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
  
 0.719
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.616
EEZ61281.1
HAD hydrolase, family IB; KEGG: rha:RHA1_ro02056 2.3e-15 possible phosphoserine phosphatase K01079; Psort location: Cytoplasmic, score: 8.87.
   
 0.575
cysK
Cysteine synthase A; KEGG: bfr:BF4576 2.4e-107 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.566
ilvN
KEGG: mma:MM0669 5.0e-43 acetolactate synthase small subunit K01653; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.551
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.