STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdaAAL-serine dehydratase, iron-sulfur-dependent, alpha subunit; KEGG: tte:TTE1009 4.3e-60 sdaA2; L-serine deaminase K01752; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family. (569 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.957
EEZ61403.1
KEGG: sfu:Sfum_2682 8.7e-62 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.98.
     
 0.891
EEZ60993.1
KEGG: chy:CHY_1912 2.3e-93 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.888
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.873
ilvA
KEGG: fnu:FN1411 1.3e-113 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.850
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.812
EEZ61396.1
Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: sgl:SG1466 1.3e-06 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.
  
  
 0.769
EEZ61685.1
Aldehyde dehydrogenase (NAD) family protein; KEGG: fnu:FN0454 3.9e-169 aldehyde dehydrogenase B K00138; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.717
cysK
Cysteine synthase A; KEGG: bfr:BF4576 2.4e-107 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.646
EEZ62274.1
CBS domain protein; KEGG: mta:Moth_2414 2.8e-65 inorganic diphosphatase K01507; Psort location: Cytoplasmic, score: 8.87.
       0.604
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.