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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaAGMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. (530 aa)    
Predicted Functional Partners:
EEZ61499.1
KEGG: lwe:lwe0114 9.9e-212 inosine-5-monophosphate dehydrogenase, putative K00088; Psort location: Cytoplasmic, score: 8.87.
 
 0.998
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.989
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.977
EEZ61396.1
Drug resistance MFS transporter, drug:H+ antiporter-2 family; KEGG: sgl:SG1466 1.3e-06 dethiobiotin synthase K01935; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the major facilitator superfamily.
  
 0.966
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.959
EEZ60515.1
KEGG: blo:BL1108 0. purL; phosphoribosylformylglycinamidine synthase K01952; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.959
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 0.955
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
 0.954
lysS
lysine--tRNA ligase; KEGG: sha:SH2493 5.2e-135 lysS; lysyl-tRNA synthetase class II K04567; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.951
hpt
KEGG: mle:ML0214 2.8e-49 hpt; putative hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.950
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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