STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ61281.1HAD hydrolase, family IB; KEGG: rha:RHA1_ro02056 2.3e-15 possible phosphoserine phosphatase K01079; Psort location: Cytoplasmic, score: 8.87. (250 aa)    
Predicted Functional Partners:
hisE
phosphoribosyl-ATP diphosphatase; KEGG: bha:BH3577 1.2e-55 hisI; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase K01496:K01523; Psort location: Cytoplasmic, score: 9.98; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.947
EEZ60650.1
Hypothetical protein; KEGG: swo:Swol_1770 3.4e-21 histidine--tRNA ligase K01891; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.816
agcS
Amino acid carrier protein; KEGG: hpa:HPAG1_0925 1.6e-83 D-alanine glycine permease K01613; Psort location: CytoplasmicMembrane, score: 10.00.
       0.773
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.710
hisB
KEGG: mta:Moth_2034 4.3e-53 imidazoleglycerol-phosphate dehydratase K01693; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.674
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.652
EEZ62089.1
KEGG: lxx:Lxx15520 3.1e-25 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.642
hisA
KEGG: syc:syc2265_c 1.3e-49 hisA; phosphorybosilformimino-5-amino- phosphorybosil-4-imidazolecarboxamideisomerase K01814; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.642
hisC
Putative histidinol-phosphate transaminase; KEGG: dar:Daro_3383 4.8e-77 histidinol-phosphate aminotransferase K00817; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
  
 0.606
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.590
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.