STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEZ61358.1Hypothetical protein; KEGG: pca:Pcar_2722 2.6e-19 5-methyltetrahydrofolate-homocysteine methyltransferase, truncation K00548; Psort location: Cytoplasmic, score: 8.87. (297 aa)    
Predicted Functional Partners:
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
  
 0.918
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.908
EEZ60993.1
KEGG: chy:CHY_1912 2.3e-93 hom; homoserine dehydrogenase K00003; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.908
cysK
Cysteine synthase A; KEGG: bfr:BF4576 2.4e-107 cysteine synthase A K01738; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.907
EEZ60557.1
Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 2.3e-93 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.906
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.904
fhs
KEGG: spb:M28_Spy1758 8.6e-197 fhs.2; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.898
EEZ61380.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bfr:BF3545 2.7e-161 O-acetylhomoserine (thiol)-lyase K01740; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.893
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: gme:Gmet_2905 1.3e-140 AICARFT/IMPCHase bienzyme:MGS-like K00602:K01492; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.891
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
     
 0.891
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.