STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)    
Predicted Functional Partners:
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; KEGG: chy:CHY_1999 6.1e-164 oadA; oxaloacetate decarboxylase, alpha subunit K01571; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.999
EEZ61598.1
Putative biotin--[acetyl-CoA-carboxylase] ligase; KEGG: ace:Acel_0398 2.0e-17 biotin--acetyl-CoA-carboxylase ligase K01947; Psort location: Cytoplasmic, score: 8.87.
    
 0.975
EEZ60663.1
Putative [acyl-carrier-protein] S-malonyltransferase; KEGG: stl:stu0386 2.1e-42 fabD; malonyl CoA-ACP transacylase K00645; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.974
EEZ61780.1
AMP-binding enzyme; KEGG: bpm:BURPS1710b_A2151 9.8e-81 pchF; pyochelin synthetase K01932; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.954
EEZ61781.1
Phosphopantetheine attachment domain protein; KEGG: rha:RHA1_ro00144 1.1e-05 non-ribosomal peptide synthetase K01779:K03367; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.954
leuA
Putative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.953
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737.
   
 0.952
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.941
fabF
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.938
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.