STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folPDihydropteroate synthase; KEGG: rso:RSc1527 1.6e-60 folP, RS03777; probable 7,8-dihydropteroate synthase protein K00796; Psort location: Cytoplasmic, score: 8.87. (435 aa)    
Predicted Functional Partners:
folC
Bifunctional protein FolC; KEGG: tte:TTE0783 7.2e-74 folC; Folylpolyglutamate synthase K01930; Psort location: Cytoplasmic, score: 8.87.
 
 0.999
folB
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.994
folE
GTP cyclohydrolase I; KEGG: cno:NT01CX_0377 2.1e-60 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.87.
 
 0.991
EEZ61783.1
Putative (2,3-dihydroxybenzoyl)adenylate synthase; KEGG: bce:BC2304 3.5e-90 2,3-dihydroxybenzoate-AMP ligase K02312; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.917
ilvE
KEGG: cac:CAC1479 2.0e-117 ilvE; branched-chain-amino-acid transaminase (ilvE) K00826; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.911
EEZ61598.1
Putative biotin--[acetyl-CoA-carboxylase] ligase; KEGG: ace:Acel_0398 2.0e-17 biotin--acetyl-CoA-carboxylase ligase K01947; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.889
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.803
hflB
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.789
EEZ61547.1
Hypothetical protein; KEGG: ctc:CTC02272 1.3e-21 purine nucleoside phosphorylase K00755; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.767
EEZ61597.1
MATE efflux family protein; KEGG: pca:Pcar_2001 0.00030 vacuolar-type H+-pyrophosphatase K01507; Psort location: CytoplasmicMembrane, score: 9.99.
     
 0.734
Your Current Organism:
Slackia exigua
NCBI taxonomy Id: 649764
Other names: S. exigua ATCC 700122, Slackia exigua ATCC 700122, Slackia exigua str. ATCC 700122, Slackia exigua strain ATCC 700122
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.